Saturday, April 23, 2011

info on drug trial

Here is a link to the Resveratrol drug trial being conducted in
Australia. A recent email discussion with Assoc/ Professor Delatycki
told me, he is confident on achieving the number of participants
required from the local FAers, and at this stage will not be seeking
beyond the borders of the state of Victoria, due mainly to the servicing
needs of the trial.

Still it is interesting to read about it, and know what is going on.

http://www.clinicaltrials.gov/ct2/show/NCT01339884?term=friedreich%27s
+ataxia&rcv_d=14

Saturday, April 16, 2011

multiple research links

Hi everyone,

sorry for this long list, but here are many research links I have been
sent... thanks Juan Carlos for these.

Thursday, March 10, 2011
Clinical proof of concept patient trials for OX1 in Friedreich's Ataxia
http://www.stockwatch.com/News/Item.aspx?bid=U-z0215942-U:ILNS-20110310&symbol=ILNS&news_region=U

Friday, March 11, 2011
Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors
ameliorates the disease phenotype of a Friedreich ataxia mouse model
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNK-52BWVTY-1&_user=10&_coverDate=03/10/2011&_rdoc=1&_fmt=high&_orig=&_origin=&_zone=rslt_list_item&_cdi=6965&_sort=d&_docanchor=&view=c&_ct=1&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=68821aec88d51668f3e40c83cbb76948&searchtype=a

Saturday, March 12, 2011
A Combined Nucleic Acid and Protein Analysis in Friedreich Ataxia:
Implications for Diagnosis, Pathogenesis and Clinical Trial Design

http://www.plosone.org/article/info%3Adoi%2F10.1371%
2Fjournal.pone.0017627

Saturday, March 12, 2011
Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month
phase III study (IONIA).
http://www.ncbi.nlm.nih.gov/pubmed/21392622?dopt=Abstract

Tuesday, March 15, 2011
Protein That Keeps Brain Signals Intact Yields Clue To Disorders
http://www.medicalnewstoday.com/articles/219095.php

Sunday, March 27, 2011

Stem Cell Research May Lead To New Treatments For Parkinson's Disease,
Huntington's Disease, Multiple Sclerosis, Stroke, Spinal Cord Injury
http://www.medicalnewstoday.com/articles/220332.php

Friday, April 1, 2011
Mitochondrial iron trafficking and the integration of iron metabolism
between the mitochondrion and cytosol
http://www.authorstream.com/Presentation/jaya85-925285-mitochondrail-iron-trafficking/

Monday, April 4, 2011
Younger Cardiac Patients Benefit From Hypothermia Therapy
http://www.medicalnewstoday.com/articles/221123.php

Tuesday, April 5, 2011
Patient's Own Cells May Hold Therapeutic Promise After Reprogramming,
Gene Correction
http://www.sciencedaily.com/releases/2011/04/110404151347.h

Wednesday, April 6, 2011
Could thiazolidinediones increase the risk of heart failure in
Friedreich's ataxia patients?

http://onlinelibrary.wiley.com/doi/10.1002/mds.23711/abstract;jsessionid=85AAD38E8ACE56903BE89978813732BF.d01t03

Wednesday, April 6, 2011
Modern Surgery For Scoliosis Has Good Long-Term Outcomes

http://www.medicalnewstoday.com/articles/221373.php

Thursday, April 7, 2011
New Method Delivers Drug to the Brain
http://friedreichscientificnews.blogspot.com/2011/04/new-method-delivers-drug-to-brain.html

Tuesday, April 12, 2011
Intellect Neurosciences Files Orphan Drug Application in the United
States for Its Clinical Candidate OX1 for the Treatment of Friedreich's
Ataxia
http://www.streetinsider.com/Press+Releases/Intellect+Neurosciences
+Files+Orphan+Drug+Application+in+the+United+States+for+Its+Clinical
+Candidate+OX1+for+the+Treatment+of+Friedreichs+Ataxia/6422856.html

Saturday, April 16, 2011
Infectious delivery and long-term persistence of transgene expression in
the brain by a 135-kb iBAC-FXN genomic DNA expression vector.
http://www.ncbi.nlm.nih.gov/pubmed/21490681?dopt=Abstract

Saturday, April 16, 2011
Project title: Characterising gait and upper limb disorder in Friedreich
ataxia
http://www.med.monash.edu.au/psych/students/scholarships.html

Friday, April 15, 2011

A note from FARA(A) President Mike Dwyer

Hi,
here is a link to a press release earlier this year, with announcements
and news from new FARA(A) president Mike Dwyer

http://www.fara.org.au/PRES2011.html

Wednesday, April 6, 2011

NAF conference downloads

Hi everyone,

I am planning on writing a summary on the NAF conference for you all....
just processing it:-> In the meantime, here is a web page with the
presentations to download.
http://www.ataxia.org/events/2011-amm-presentations.aspx

Cheers

Laurel